| 12 Sep 2026 | 14:00 | League One | Sheffield Wednesday vs Wigan | Hillsborough |
| 19 Sep 2026 | 14:00 | League One | Sheffield Wednesday vs Stockport County | Hillsborough |
| 22 Sep 2026 | 18:00 | EFL Trophy | Salford City vs Sheffield Wednesday | Peninsula Stadium |
| 26 Sep 2026 | 14:00 | League One | Stevenage vs Sheffield Wednesday | Lamex Stadium |
| 3 Oct 2026 | 14:00 | League One | Sheffield Wednesday vs Cambridge United | Hillsborough |
| 6 Oct 2026 | 18:00 | EFL Trophy | Sheffield Wednesday vs Sunderland U21 | Hillsborough |
| 10 Oct 2026 | 14:00 | League One | Huddersfield vs Sheffield Wednesday | Accu Stadium |
| 17 Oct 2026 | 14:00 | League One | Sheffield Wednesday vs AFC Wimbledon | Hillsborough |
| 20 Oct 2026 | 18:45 | League One | Notts County vs Sheffield Wednesday | Meadow Lane |
| 24 Oct 2026 | 14:00 | League One | Doncaster vs Sheffield Wednesday | Eco-Power Stadium |
| 1 Nov 2026 | 14:00 | League One | Sheffield Wednesday vs Blackpool | Hillsborough |
| 10 Nov 2026 | 19:00 | EFL Trophy | Sheffield Wednesday vs Accrington ST | Hillsborough |
| 14 Nov 2026 | 15:00 | League One | Sheffield Wednesday vs Plymouth | Hillsborough |
| 20 Nov 2026 | 20:00 | League One | Barnsley vs Sheffield Wednesday | Oakwell |
| 28 Nov 2026 | 15:00 | League One | Sheffield Wednesday vs Reading | Hillsborough |
| 1 Dec 2026 | 19:45 | League One | Oxford United vs Sheffield Wednesday | Kassam Stadium |
| 10 Dec 2026 | 20:00 | League One | Leicester vs Sheffield Wednesday | King Power Stadium |
| 19 Dec 2026 | 12:30 | League One | Sheffield Wednesday vs Luton | Hillsborough |
| 26 Dec 2026 | 15:00 | League One | Burton Albion vs Sheffield Wednesday | Pirelli Stadium |
| 29 Dec 2026 | 19:45 | League One | Sheffield Wednesday vs Mansfield Town | Hillsborough |
| 1 Jan 2027 | 15:00 | League One | Sheffield Wednesday vs Huddersfield | Hillsborough |
| 9 Jan 2027 | 15:00 | League One | Luton vs Sheffield Wednesday | Kenilworth Road |
| 16 Jan 2027 | 15:00 | League One | AFC Wimbledon vs Sheffield Wednesday | The Cherry Red Records Stadium |
| 19 Jan 2027 | 19:45 | League One | Sheffield Wednesday vs Notts County | Hillsborough |
| 23 Jan 2027 | 15:00 | League One | Sheffield Wednesday vs Doncaster | Hillsborough |
| 30 Jan 2027 | 15:00 | League One | Blackpool vs Sheffield Wednesday | Bloomfield Road |
| 6 Feb 2027 | 15:00 | League One | Bromley vs Sheffield Wednesday | Hayes Lane |
| 9 Feb 2027 | 19:45 | League One | Sheffield Wednesday vs Wycombe | Hillsborough |
| 13 Feb 2027 | 15:00 | League One | Sheffield Wednesday vs Peterborough | Hillsborough |
| 20 Feb 2027 | 15:00 | League One | Wigan vs Sheffield Wednesday | The Brick Community Stadium |
| 27 Feb 2027 | 15:00 | League One | Plymouth vs Sheffield Wednesday | Home Park |
| 6 Mar 2027 | 15:00 | League One | Sheffield Wednesday vs Leyton Orient | Hillsborough |
| 13 Mar 2027 | 15:00 | League One | Bradford vs Sheffield Wednesday | Valley Parade |
| 20 Mar 2027 | 15:00 | League One | Sheffield Wednesday vs Barnsley | Hillsborough |
| 26 Mar 2027 | 15:00 | League One | Milton Keynes Dons vs Sheffield Wednesday | Stadium MK |
| 29 Mar 2027 | 14:00 | League One | Sheffield Wednesday vs Burton Albion | Hillsborough |
| 3 Apr 2027 | 14:00 | League One | Mansfield Town vs Sheffield Wednesday | One Call Stadium |
| 10 Apr 2027 | 14:00 | League One | Sheffield Wednesday vs Leicester | Hillsborough |
| 13 Apr 2027 | 18:45 | League One | Sheffield Wednesday vs Stevenage | Hillsborough |
| 17 Apr 2027 | 14:00 | League One | Stockport County vs Sheffield Wednesday | Edgeley Park |
| 24 Apr 2027 | 14:00 | League One | Sheffield Wednesday vs Milton Keynes Dons | Hillsborough |
| 27 Apr 2027 | 18:45 | League One | Cambridge United vs Sheffield Wednesday | Abbey Stadium |
| 1 May 2027 | 14:00 | League One | Reading vs Sheffield Wednesday | Select Car Leasing Stadium |
| 8 May 2027 | 11:30 | League One | Sheffield Wednesday vs Oxford United | Hillsborough |
